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Vastarel (Trimetazidine MR) is an anti-anginal, or anti-ischemic, metabolic agent. It helps your body to use myocardial glucose more effectively by inhibiting fatty acid metabolism, as well as preventing fatty acid oxidation in your blood vessels. When your cells are exposed to hypoxia, a deprivation of oxygen, or ischemia, a restriction in blood supply, usually due to problems with the blood vessels, your cellular homeostasis, or stability, is threatened. Vastarel (Trimetazidine MR) prevents the levels of adenosine triphosphate from dropping in your cells, allowing them to function properly, which keeps your blood pressure at a steady rate, and also keeps blood and oxygen flowing throughout your body.

Vastarel (Trimetazidine MR) is particularly useful in the treatment of angina pectoris. Commonly known simply as “angina,” angina pectoris is characterized by a sharp pain in the chest. This pain is caused by ischemia of the heart, usually due to an obstruction or spasm in a coronary artery. Coronary artery disease is the most common cause of angina pectoris. This can usually be traced back to atherosclerosis of the coronary arteries, or a thickening in the artery walls due to the building up of fatty materials. Vastarel (Trimetazidine MR) can increase the coronary flow reserve, allowing the patient to maintain a normal blood pressure and heart rate.

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