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Generic Name: Vincristine

Vincristine is used in the treatment of a variety of cancers, especially childhood cancers. It is administered in a doctor’s office, clinic, or hospital setting via an IV infusion. Cancers such as leukemias and lymphomas are the most common cancers treated with Vincristine. It is a chemotherapy medication that acts by slowing the growth of cancer cells as they go through division into two cells. If cancer cells experience interference in their growth, especially as division is occurring, they usually die, thus preventing or at least slowing the spread of cancerous cells.

Since Vincristine, a vinca alkaloid, is administered through an IV infusion, your doctor will be able to monitor exact dosage and times required. As such, do not miss an appointment with your physician during the course of your cancer treatment. As with any cancer treatment, some side effects are expected. Discuss side effects with your physician to determine what can be done to alleviate symptoms, or if side effects warrant stopping treatment with Vincristine. The most common side effects are nausea, mouth sores, or constipation. Your doctor may prescribe medications to help with these side effects.

Vincristine can lower white cell counts, thus increasing your risk of infection. As such, do not have vaccinations or stay away from people who have recently been vaccinated or who exhibit signs of contagious illness while undergoing treatment with Vincristine. Additionally, your doctor will test kidney and liver function before, during, and after Vincristine treatments to ensure the medication is not unduly harming organ function. Since blood platelets are also affected by treatment with Vincristine, be aware that bleeding problems may occur. It may be harder to stop bleeding from a cut or sore while undergoing treatment. Consult with your doctor or health care provider about precautions you should take while being treated with Vincristine.

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