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What is Aptiom?

Aptiom – also known by its generic name eslicarbazepine – is an anticonvulsant (anti-seizure) medication.

Although its exact mechanism of action is not yet fully understood, Aptiom works by reducing the excessive nerve impulses in the brain that cause seizures.

Despite the many anti-seizure medications already available, seizures remain poorly controlled in about a third of people with epilepsy. As such, the arrival of novel therapies such as Aptiom is a welcome development.

Condition Treated by Aptiom

Aptiom is used to treat partial-onset seizures in adults and children age 4 and up. It may be used on its own or as an add-on with other anti-seizure medications.

Aptiom Side Effects

Aptiom is generally well tolerated, but may cause side effects. As a medication that works primarily on the brain, it is not surprising that its most common side effects are brain-related: dizziness, headache, and double vision. Other common Aptiom side effects may include: blurry vision, nausea or vomiting, diarrhea, abdominal pain, sleepiness, and poor coordination or balance.

Aptiom, like other anti-seizure medications, is associated with an increased risk of suicidal thoughts or behaviors. This potential Aptiom side effect risk arises as early as one week after starting therapy and continues during the entire period of treatment.

Some people may develop a hypersensitivity (allergic) reaction to Aptiom. Serious and even fatal skin reactions to Aptiom may occur. Rare cases of serious allergic reactions known as anaphylaxis and angioedema have also been reported. A multi-organ hypersensitivity syndrome known as "DRESS," a potentially life-threatening condition, has also been reported.

People taking Aptiom may develop significant sodium deficiencies, and may require routine blood testing to monitor their blood sodium levels.

Routine blood tests are recommended before and during treatment as Aptiom may cause liver or thyroid problems.

What you Should Know Before Using Aptiom

When discontinuing Aptiom medication, the dose should be tapered down gradually so as to avoid the risk of seizures or status epilepticus (persistent, non-stop seizures) with abrupt discontinuation of the drug.

People who are considering Aptiom medication should be sure to tell their prescriber if they have ever had kidney disease, liver disease, depression, or suicidal thoughts.

Aptiom may interfere with the effectiveness of the birth control pill, so women who require birth control should use an alternative non-hormonal method.

Not enough is known about the effects of Aptiom on pregnancy and the fetus to provide an estimate of the risk of adverse effects when taking Aptiom during pregnancy. Likewise, although Aptiom is known to be excreted in the breast milk, Aptiom side effects on the baby or on milk production are not known. As such, women who are pregnant or may become pregnant, and breastfeeding women, should discuss the use of Aptiom with their doctor.

Tell your doctor about all prescription and over-the-counter medications that are being used while taking Aptiom. Certain medications, such as oxcarbazepine, carbamazepine, simvastatin, omeprazole, clobazam, phenobarbital, phenytoin, birth control medicine, rosuvastatin, and primidone are known to interact with Aptiom.

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