Description of DDAVP Injection

DDAVP stands for Deamino-d-arginine vasopressin and is available as an injection for individuals that are lacking a certain hormone that can reduce your urine output. The body contains a natural chemical called vasopressin that helps to regulate urine production, kidney function, blood flow and blood pressure. Certain types of head trauma or brain surgery may disrupt the production of vasopressin from the pituitary gland.

This antidiuretic hormone or ADH may also be prescribed for treating central diabetes insipidus which can be caused by a lack of the hormone that normally limits the amount of urine your body produces. Although diabetes mellitus and diabetes insipidus are similar in name and associated with increased thirst and urination, they are very different conditions.

How DDAVP Injection Works

DDAVP Injection (Desmopressin) works by binding to the ADH receptors in your kidneys, which mimics the effect of natural ADH and reduces the production of urine. This method of using Desmopressin Injection works by injecting the synthetic hormone solution into the muscle or deep under your skin, allowing it to increase the appearance of this particular hormone in the body. This hormone is important to blood flow, water regulation, blood pressure, and kidney function, and DDAVP Injection therapy helps to ensure your body has enough of the hormone to handle these functions properly.

Other Conditions Treated by DDAVP Injection

In the condition diabetes insipidus, the kidneys produce excessive quantities of very dilute urine which causes excessive thirst and can lead to dehydration. Diabetes insipidus can be caused by a problem with the kidneys themselves or through a deficiency in the production of ADH by the pituitary gland.

DDAVP Injection is also prescribed for the treatment of hemophilia or Von Willibrand’s disease in which there is either a deficiency or a lack of some clotting factors that can create problems with stopping bleeding. Von Willibrand’s disease is passed on from parent to child and there is genetic testing available to determine if you or a family member is carrying the gene.

Some doctors may suggest DDAVP Injection therapy to prevent excessive night time urination in people with multiple sclerosis (MS) when other treatments for this have been unsuccessful.

Before You Use DDAVP Injection

Ask your doctor if a DDAVP Injection is safe to have if you are pregnant, trying to conceive, or are breast feeding. Your doctor should be made aware of other medical conditions you have, including cardiovascular disease, decreased kidney function, or cystic fibrosis before starting DDAVP Injections.

List all OTC and Rx drugs, herbal remedies, and vitamin supplements you currently take or use as there is a risk of water retention if you are taking certain medications, such as non-steroidal anti-inflammatory drugs and antidepressants.

Precautions for DDAVP Injection

You must avoid excessive fluid intake if you are taking Desmopressin regularly as this can lead to a build- up of fluid in your body. Do not stop, start, or alter the dosage of any medications without talking to your doctor first.

Possible Side Effects of DDAVP Injection

• Headache
• Nausea
• Stomach pain

Drugs Similar to DDAVP Injection

• DDAVP Spray
• DDAVP tablets