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Buy Depo-Medrol Online

A prescription is required for this item.
No generic alternative is available at this time.
BRAND LISTING - Depo-Medrol (Methylprednisolone)
Dosage Pack Size & Price Qty
20mg/mL (1 x 5mL vial)
40mg/mL ( 1 x 1mL vial)
40mg/mL (10 x 1mL vials)
40mg/mL (10 x 2mL vials)
40mg/mL (10 x 3mL vials)
40mg/mL (5 x 2mL vials)
40mg/mL (5 x 5mL vials)
80mg/mL (1 x 5mL vial)
80mg/mL (5 x 1mL vials)


A Description of Depo-Medrol

Depo-Medrol is a corticosteroid drug administered by a doctor for treating a variety of inflammatory conditions and diseases to keep you as comfortable as possible as the symptoms are decreased. These include ulcerative colitis, Crohn’s disease, allergic reactions, skin/eyes/blood diseases, arthritis, and primary or secondary adrenocortical insufficiency. The Depo-Medrol injection may be given into a muscle (intramuscular), into a joint (intra-articular), or directly into the lesion or into the skin below the lesion (intralesional).

How the Active Ingredient Methylprednisolone Works

The active ingredient in Depo-Medrol is a corticosteroid called Methylprednisolone. Once your doctor injects Depo-Medrol into a muscle, joint, soft tissue, or lesion, the corticosteroid will act to stop the production of certain chemicals that cause inflammation as an immune response to a threat or injury. To do this, Methylprednisolone will cause proteins to block the chemical that plays a role in your inflammatory response so your inflammation is decreased as your immune system becomes suppressed.

Arthritis is a Popular Reason for Depo-Medrol Injections

Rheumatoid arthritis is an autoimmune disease that involves your own immune system attacking the cartilage and joint lining in your fingers, wrists, knees, or elbows. This can make grasping, bending, reaching, and walking painful as you lose the cushioning effect that allows smooth movements when you use the affected joints. Therapy with injections of Depo-Medrol can reduce the inflammation and provide you comfort while performing daily tasks without pain and swelling.

Before You Start Depo-Medrol Injections

Ask your doctor if Depo-Medrol is safe to use if you are pregnant, trying to conceive, or are breast feeding. Your doctor should know about other medical conditions or allergies you have and list all OTC and Rx medications you currently take or use, including herbal remedies and dietary or vitamin supplements. This will help to determine if Depo-Medrol injections are the right treatment for your situation.

Precautions About the Use of Depo-Medrol

Long-term use of corticosteroids may be a necessary part of your life when experiencing an unforgiving disease such as arthritis, but with a suppressed immune system you can be at the mercy of other infections or diseases. It can also cause your own adrenal glands to cut back on the production of your own corticosteroid called cortisol. If you suddenly stop Depo-Medrol injections, you may have to give the adrenal glands time to regain full function to start producing cortisol as it should.

Possible Side Effects of Depo-Medrol

  • Headache
  • Mood changes
  • Dizziness
  • Fluid retention

Other Anti-inflammatory Drugs Similar to Depo-Medrol

The information provided on the website is intended to facilitate awareness about healthcare products and medical conditions generally but it is not a substitute for professional medical attention or advice. You should always speak with a qualified healthcare practitioner before taking any prescription or non-prescription drug.