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Buy Entresto Online

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No generic alternative is available at this time.
BRAND LISTING - Entresto (Sacubitril/Valsartan)
Dosage Pack Size & Price Qty
Product description written by Dr. Ami Patel, PharmD (Feb 4, 2020)

What is Entresto?

Entresto (generic name sacubitril and valsartan) is a medicine used to help people with a weak heart and a condition called chronic heart failure. Chronic heart failure is a long-lasting disease that occurs when the heart is weak and cannot pump enough blood around the body and lungs.

Entresto can help keep you out of the hospital by making it easier for your heart to pump blood around the body.

If chronic heart failure is not treated, it can leave you feeling tired and short of breath because your lungs cannot work well when your heart is weak. Sometimes fluid can spill into your lungs and make you cough, or make it hard to breathe. It can also lead to swelling in your legs and feet. Sometimes the swelling becomes serious and results in weight gain.

What is Entresto used for?

Entresto is used to treat a certain type of chronic heart failure in which your heart becomes larger and weaker. It is used in adults and children over 1 year old.

What are possible Entresto side effects?

Entresto side effects include:

  • A rare, but serious allergic reaction called angioedema. You may have trouble breathing because your throat, tongue, lips, and face become swollen.

  • Low blood pressure – feeling lightheaded, tired or dizzy (this is more common if you use water pills, such as HCTZ or hydrochlorothiazide, Lasix or furosemide, among others)

  • High potassium in your blood – feeling like your heart is racing or skipping a beat; your doctor can test your blood while taking this medicine to prevent Entresto side effects

  • A dry, persistent cough

  • Dizziness

  • Kidney trouble- your doctor can run blood tests to make sure you kidneys stay healthy while using Entresto

What you should know before taking Entresto?

Do not use Entresto if you are pregnant, or planning to become pregnant. Entresto may hurt or kill an unborn child. It is not safe to use in children under one year old. Do not use Entresto if you are breastfeeding, or planning to breastfeed.

Do not use Entresto if you're allergic to any of the ingredients in Entresto. Do not use Entresto if you have diabetes and you take medicine containing aliskiren, such as Amturnide Tekturna, Tekturna HCT, Tekamlo, or Valturna.

Do not take Entresto if you're using an ACE inhibitor (such as lisinopril or enalapril, among others). Talk to your doctor to be sure you are not currently taking an ACE inhibitor. Stop your ACE inhibitor, then wait at least 36 hours before taking Entresto.

Do not use Entresto if you have ever had an allergic reaction where your tongue, throat, face, or lips swelled up (or if you had trouble breathing) after using an ACE inhibitor or ARB medication. Talk to your doctor to be sure you never had a reaction to an ACE inhibitor or ARB medication

If you have a family history of hereditary angioedema (a condition where your tongue, tongue, throat, face, and lips swell up, or if you had trouble breathing) then do not use Entresto.

Tell your doctor if you have kidney or liver problems before you start Entresto. Your doctor will check your blood to make sure your kidneys and liver are well before starting Entresto. They will also run blood tests while you are taking Ernesto to make sure your kidneys and liver remain healthy.

Using Entresto with other medications can cause dangerous and possibly deadly side effects. Prevent Entresto side effects by telling your doctor if you use any of the following medications:

  • NSAIDS such as ibuprofen (Motrin/Advil) and naproxen (Aleve) among others
  • Lithium (Eskalith or Lithobid among others)
  • Potassium pills or powder (like K-Dur, or vitamins) or salt substitutes (such as NuSalt, and NOSalt, among others)
  • ACE inhibitors (such as Lisinopril, enalapril, and benazepril, among others)
  • ARB medicines (such as Losartan and Valsartan, among others)

Show your doctor any medicines you are currently using, and tell the doctor if you're planning to start any new medicine or over-the-counter supplements while taking Entresto.


  • How long does it take for Entresto to work?
  • How much does Entresto cost?
  • What is the proper dosage for Entresto?
  • The information provided on the website is intended to facilitate awareness about healthcare products and medical conditions generally but it is not a substitute for professional medical attention or advice. You should always speak with a qualified healthcare practitioner before taking any prescription or non-prescription drug.