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Buy Motegrity or Generic Prucalopride Online

A prescription is required for this item.
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BRAND LISTING - Motegrity (also known as Resolor) (Prucalopride)
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Product description written by Dr. Ami Patel, PharmD (Mar 12, 2020)

What is Motegrity?

Motegrity (generic name Prucalopride) is a medicine used to treat a certain type of constipation. Constipation is defined as hard, dry, and difficult to pass stools (poop). Motegrity treats constipation that has no known cause. It's used for chronic (long-term) constipation that has lingered for more than six months. Motegrity helps the muscles in your gut move stool through your body so that you can poop more frequently and easily.

What is Motegrity used for?

Motegrity is used in adults to treat long-term constipation that has no known cause. Unlike laxative medicines that just add liquid to your stools, Motegrity can actually help your gut muscles move stool quicker through your body

What are possible Motegrity side effects?

The most common side effects of Motegrity include:

  • Diarrhea (loose, or frequent stools)

  • Headache

  • Belly pain

  • Feeling nauseous or sick to your stomach

  • Bloating

  • Feeling dizzy

  • Throwing up

  • Feeling gassy

  • Feeling tired

Uncommon, less frequently observed Motegrity side effects include:

  • Frequent urination (peeing more often than normal)

  • Loss of appetite

  • Migraine headache

  • Unusual digestion noises (stomach growling sounds)

A serious Motegrity side effect is the worsening of depression. In some people, Motegrity may affect mood and can make you feel sad or depressed. Occasionally, this may lead to suicidal thoughts or ideas of trying to hurt yourself. If you have a history of depression (sadness), anxiety (being worried), or feeling hopeless, then do not use Motegrity. If you start noticing any changes in your mood after starting Motegrity, then call your doctor immediately and stop using Motegrity right away.

Occasionally, people may experience an allergic reaction to Motegrity. This can cause a rash, or itching and swelling of your face, tongue, or lips, as well as trouble breathing.

What should you know before taking Motegrity?

Do not use Motegrity if you're allergic to any of the ingredients in Motegrity.

Motegrity is not for children. Do not use Motegrity if you're pregnant or planning to become pregnant. Motegrity can pass into breastmilk, so do not use Motegrity if you're breastfeeding or planning to breastfeed. Tell your doctor if you have kidney problems before you start using Motegrity. Motegrity is not safe for people with a tear in the stomach or intestines (also known as a bowel perforation). It should not be used in people with a bowel blockage (also known as an obstruction). Do not use Motegrity if you have serious intestinal problems (such as Chron's disease or Ulcerative Colitis).

Tell your doctor about all other prescription and over-the-counter medicines you use before starting Motegrity. Tell your doctor if you are using or planning to use ketoconazole or erythromycin while on Motegrity.

Drugs Similar to Motegrity

  • Amitiza (Lubiprostone)
  • Generlac Solution (Lactulose)
  • Kristalose(Lactulose)
  • Lactulose Laxative(Lactulose )
  • Linzess (Linaclotide)
  • PegLyte Fruit Flavoured Powder (Macrogol/Potassium Chloride/Sodium Bicarbonate/Sodium Chloride/Sodium Sulfate)
  • Polyethylene Glycol (Polyethylene Glycol)
  • Reglan (Metoclopramide)


  • How long does it take for Motegrity to work?

    In most people, Motegrity can start working within 2 to 3 hours, however your first full bowel movement may not occur until after you use Motegrity regularly for at least 5 days.

  • What is the proper dosage for Motegrity?

    The dosage for Motegrity must be personalized based on why you are taking Motegrity and how well your kidneys work. Follow the instructions provided by your doctor. For most people, the typical Motegrity dosage is to swallow one tablet once daily at the same time each day.

  • How much does Motegrity cost?

    Since Motegrity is only available as a brand-name medication, it can be expensive. Motegrity cost varies based on dosage and the way it's prescribed by your doctor. carries Motegrity at a more reasonable price than most pharmacies.

  • The information provided on the website is intended to facilitate awareness about healthcare products and medical conditions generally but it is not a substitute for professional medical attention or advice. You should always speak with a qualified healthcare practitioner before taking any prescription or non-prescription drug.