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Buy Otezla Online

A prescription is required for this item.
Dosage Pack Size & Price Qty
BRAND LISTING - Otezla (Apremilast)
Dosage Pack Size & Price Qty
Starter Kit (10mg/20mg/30mg)

The generic alternative is not manufactured by the company that makes the brand product.

How to Buy Prescription Drugs Online

Product description written by Dr. Amanda Jacot, PharmD (January 24, 2023)

What is Otezla?

Otezla works inside the body to reduce inflammation.

Some conditions, like psoriasis, are associated with overactive inflammation. It is thought that inflammation is partially caused by an enzyme found inside inflammatory cells called phosphodiesterase-4 (PDE4).

Otezla is known as a PDE4 inhibitor because it blocks PDE4 activity. When the PDE4 enzyme is blocked, it is can decrease overactive inflammation. Less inflammation means fewer symptoms for many people.

Otezla is also known by its generic name, Apremilast.

What is Otezla used for?

Otezla is used to decrease inflammation all over the body in people with conditions caused by an overactive immune system.

Otezla has been approved by the U.S. Food and Drug Administration (FDA) to treat adults with:

  • Active psoriatic arthritis
  • Plaque psoriasis who are candidates for phototherapy or systemic therapy
  • Oral ulcers associated with Behçet's disease

What are Otezla’s side effects?

Otezla may cause side effects. However, the side effects are different for everyone — some people may have few or no side effects.

The most common side effects of Otezla include:

  • Weight loss
  • Diarrhea
  • Nausea
  • Vomiting
  • Headache
  • Cold-like symptoms
  • Back pain
  • Joint pain

This is not a complete list of Otezla’s side effects; other side effects can occur. Talk to your healthcare provider if you have side effects that bother you or if they do not go away.

Even though it is rare, it is possible to experience more serious side effects while taking Otezla. Talk to your healthcare provider and get help as soon as possible if you experience any of the following side effects while you are taking Otezla:

  • Otezla can cause an allergic reaction in some people. Get help right away if you have signs of an allergic reaction like a skin rash, chest tightness, trouble breathing, or swelling in your face and mouth.
  • Although nausea, vomiting, and diarrhea are common Otezla side effects, it can be bad enough for some people that they need to go to the hospital. Call your healthcare provider if you have very bad nausea, vomiting, or diarrhea or if your symptoms do not go away after you have been using Otezla for a few weeks.
  • Otezla can increase the risk of depression. Get help if you notice new or worsening depression, mood changes, anxiety, or thoughts of hurting yourself.

What should you know before you start taking Otezla?

Before you start taking Otezla, talk to your healthcare provider about your medical history and which medications you are currently taking. You should consider the following:

Otezla can cause weight loss. Before you start taking Otezla, you should check your weight and monitor it the whole time you are taking Otezla.

Your healthcare provider may recommend a different dose of Otezla if you have kidney disease.

Otezla may harm an unborn baby. If you are pregnant, planning on becoming pregnant, or breastfeeding, talk to your healthcare provider about the possible benefits and risks to you and your baby.

People that have had depression or suicidal thoughts in the past may have a higher risk of new or worsening depression while using Otezla.

Individuals who are 65 years or older may have more side effects.

You should not take Otezla if you are allergic to this drug or any of the ingredients. Tell your healthcare provider about any allergies you have to drugs, food, or other substances.

Otezla uses inactive ingredients, including lactose monohydrate, microcrystalline cellulose, croscarmellose sodium, magnesium stearate, polyvinyl alcohol, titanium dioxide, polyethylene glycol, talc, and iron oxide. Do not take Otezla if you are allergic to any of these ingredients.

Otezla should not be taken with certain medications. Tell your healthcare provider about all the medications you are taking, including prescriptions, over-the-counter medicines, and supplements. Otezla is not recommended to be taken with the following medications:

  • Carbamazepine
  • Phenobarbital
  • Phenytoin
  • Rifampin
  • St. John’s wort

Otezla may decrease the effectiveness of certain vaccines, such as the COVID-19 vaccine. Your healthcare provider may recommend stopping Otezla for a short time before you get a vaccine.

Keep taking Otezla exactly as you have been told by your healthcare provider, even if you feel well. Make sure you read all of the information given to you and closely follow the instructions.

Otezla can be taken with or without food.

Otezla should be swallowed whole. You should not crush, chew, or break the tablet.


How much does Otezla cost?

A 30-day supply of Otezla costs up to several thousand dollars at your local pharmacy. However, you can buy Otezla online for a much more affordable price. offers a price guarantee to make sure you get the lowest price.

Where can I buy Otezla online?

Otezla and other medications can be purchased online from pharmacies like with a valid prescription. When you buy Otezla online, your prescription will be delivered to your door, saving you time and money.

The information provided on the website is intended to facilitate awareness about healthcare products and medical conditions generally but it is not a substitute for professional medical attention or advice. You should always speak with a qualified healthcare practitioner before taking any prescription or non-prescription drug.