For temporary relief from nasal congestion caused by a cold, sinusitis, or allergies, ask your pharmacist or doctor about Otrivin Decongestant Drops. The active ingredient in Otrivin is a decongestant called Xylometazoline and when used as directed, will constrict the blood vessels in your nasal tissues to reduce swelling and allow you to breathe easier. If after 3 days of using Otrivin Decongestant Drops you still have nasal congestion or your symptoms have worsened, see your doctor before continuing any treatments.