For the Treatment of Adrenal Insufficiency

Adrenal insufficiency is a hormonal disorder that can happen if your adrenal glands stop producing enough of your own natural hormone cortisol. This hormone is essential for helping your body deal with stress first and foremost but also helps to maintain blood pressure, the functioning of blood vessels and your heart, regulating your metabolism, and slowing your body’s inflammatory immune response.

What is Plenadren?

Plenadren is taken as a substitute for the cortisol your body is unable to produce sufficiently. The active ingredient in Plenadren is a glucocorticoid called Hydrocortisone and it is designed to be released slowly throughout your day. When you get up in the morning, take your dose of Plenadren (Hydrocortisone Modified Release) with water about half an hour before your breakfast. You should remain upright after taking Plenadren to reduce the risk of esophagitis.

Primary and Secondary Adrenal Insufficiency

Primary adrenal insufficiency indicates you have Addison’s disease. This is believed to be caused by your immune system malfunctioning as it your adrenal cortex as an intruder or threat. The damage to your adrenal cortex affects your adrenal glands and cortisol levels drop. Secondary adrenal insufficiency is when your pituitary gland, found at the base of your brain, is not able to produce another hormone known as adrenocorticotropin (ACTH). Adrenocorticotropin’s job is to stimulate your adrenal glands to produce cortisol. Without this stimulation, your adrenal glands can shrink.

Before You Start Taking Plenadren

Ask your doctor if Plenadren is safe to take if you are pregnant, trying to conceive, or are breast feeding. Discuss any pre-existing medical conditions or allergies you have and list all current over-the-counter, prescription drugs, and herbal remedies or vitamin supplements you take or use. This will help the doctor to determine if you should buy Plenadren.

Proper Use of Plenadren

Keep Plenadren and other medications out of children’s reach and do not share drugs with others. Do not split, crush, or chew the Plenadren tab as it is designed with an immediate release coating and the core is extended release which will not work as planned unless the tab is swallowed whole. Avoid taking Plenadren with grapefruit juice or grapefruit as part of your breakfast as it could affect how Plenadren will act in your body. Avoid operating a vehicle, machinery, or taking part in any activity that requires you to be alert until you know how Plenadren will affect you.

Common Side Effects That May Occur with Plenadren

• Dizziness
• Headache
• Diarrhea
• Nausea

Other Drugs Similar to Plenadren

• Decadron
• Cortef
• Kenacort