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Buy Premarin Vaginal Cream Online

A prescription is required for this item.
No generic alternative is available at this time.
BRAND LISTING - Premarin Vaginal Cream (Conjugated Estrogens)
Dosage Pack Size & Price Qty
Product description medically reviewed by Dr. Ami Patel, PharmD (Apr 16, 2020)

What is Premarin Vaginal Cream?

Premarin Vaginal Cream is a prescription medication used to manage the vaginal symptoms of menopause including atrophy, burning, dryness, irritation, and pain during sex.

The topical medication consists of conjugated estrogens, which means it contains a variety of estrogen hormones (instead of a single type). Conjugated estrogens topical creams work by supplying estrogens the body may not produce in adequate quantities as a result of menopause. This can help support and rebuild vaginal tissue.

Vaginal estrogen may be prescribed to people dealing with vaginal menopausal symptoms and/or looking to improve their sexual health (by enhancing their capacities for sexual intimacy). It may also be prescribed to people with kraurosis vulvae, a rare condition affecting the tissues around the vulva.

Drugs similar to Premarin Vaginal Cream include:

Conditions treated by Premarin Vaginal Cream

Premarin Vaginal Cream is most commonly used for the management of vaginal menopausal symptoms. As women enter and proceed through menopause, the ovaries produce less estrogen, which can lead to thinning and dryness in the vaginal tissue. This can result in a range of symptoms including vaginal atrophy, burning, dryness, irritation, and/or pain during sex.

When estrogen topical cream is inserted into the vagina, it is absorbed by the vaginal tissues. The additional estrogens can help rebuild vaginal tissue and ease some or all of the vaginal symptoms of menopause.

In some cases, Premarin Vaginal Cream may be used for the management of kraurosis vulvae, a rare disease that often corresponds with menopause and is characterized by intense itching, inflammation, and fissured tissue around the vulva. Again, supplemental estrogens may help support and rebuild this tissue.

Premarin Vaginal Cream may also be used for other purposes as determined by a medical professional.

What to know before using Premarin Vaginal Cream

Prior to using Premarin Vaginal Cream, keep the following in mind.

  • physician

    Tell your doctor about any medical conditions you might have and any medications you take so as to avoid potentially harmful interactions.

  • stroller

    Premarin Vaginal Cream is not intended for use by people who are pregnant or breastfeeding. Its use under these circumstances might harm a fetus or child.

  • prescription

    Use this medication precisely as your doctor prescribes. Make sure to clean Premarin Vaginal Cream's applicator after each use; use mild soap and warm (not hot) water.

  • heart symbol

    Be aware that Premarin Vaginal Cream can weaken latex condoms, cervical caps, and diaphragms.

  • Cigarette

    Avoid smoking while using Premarin Vaginal Cream, as smoking cigarettes can increase the risk of blood clots, heart attack, and stroke.

  • Calendar

    If you are planning to have major surgery, be aware that you may need to pause your use of this medication. Consult your doctor and surgeon about the best course of action.

  • Stop sign

    Using Premarin Vaginal Cream may increase your risk for several serious health conditions including blood clots, cancer, heart attack, and stroke. It's important to see your doctor regularly while taking this medication and self-examine your breasts for lumps at least monthly.

Possible side effects of Premarin Vaginal Cream

Potential Premarin Vaginal Cream side effects include:

  • Abdominal pain
    Abdominal pain
  • Allergic reactions
    Allergic reactions
  • Back pain
    Back pain
  • Breast pain
    Breast pain
  • Body aches
    Body aches
  • Changes in vaginal discharge
    Changes in vaginal discharge
  • Chills or fever
    Chills or fever
  • Cough and/or congestion
    Cough and/or congestion
  • Diarrhea
  • Difficulty swallowing
    Difficulty swallowing
  • Dry and/or sore throat
    Dry and/or sore throat
  • Headaches
  • Itching in the vaginal area
    Itching in the vaginal area
  • Loss of strength
    Loss of strength
  • Pain during sex
    Pain during sex
  • Painful or difficult urination
    Painful or difficult urination
  • Vaginal bleeding
    Vaginal bleeding
  • Voice changes
    Voice changes

This is not a complete list of side effects. If you experience these or any other side effects, promptly consult a medical professional.

Additionally, be aware that Premarin Vaginal Cream comes with several black box warnings, including a higher risk of breast cancer, cardiovascular issues, dementia, and endometrial cancer.

Premarin Vaginal Cream FAQs

What is the proper dosage for Premarin Vaginal Cream?

The right Premarin Vaginal Cream dosage depends on the condition and person being treated, so it's important to follow your doctor's prescribing instructions. Most commonly, a physician will prescribe 0.5 grams to be administered vaginally once per day for 21 days, followed by seven days without treatment. This cycle may be repeated for several months or more. If 0.5 grams does not prove effective, the dosage may be increased by a physician to up to 2 grams per day.

What's the best way to store Premarin Vaginal Cream?

Store this medication tightly closed at room temperature and away from direct cold, heat, light, and moisture. Keep this medication out of the reach of children and pets. Do not flush this medication down a drain or throw it in a trash can; consult a pharmacist for proper disposal instructions.

The information provided on the website is intended to facilitate awareness about healthcare products and medical conditions generally but it is not a substitute for professional medical attention or advice. You should always speak with a qualified healthcare practitioner before taking any prescription or non-prescription drug.