Synarel Nasal Solution Description

Synarel Nasal Solution is from the group of drugs called pituitary hormone analogues and is prescribed for women to treat a condition known as endometriosis. This is when the tissue that normally lines the inside of the uterus grows in other places in your body. This tissue growth is stimulated by the female hormone called estrogen.

How the Active Ingredient Called Nafarelin Works for Endometriosis

When administered nasally twice a day as directed, Nafarelin reaches your bloodstream quickly and works to decrease sex hormone secretions. In the case of endometriosis, decreasing your estrogen levels to stop the growth of this tissue, thereby relieving symptoms that may include pelvic pain, painful menstrual cramps, and pain during/after sex).

Conditions Treated by Synarel Nasal Solution

Synarel Nasal Solution may also be prescribed for treatment of central precocious puberty (CPP) (gonadotropin-dependent precocious puberty) in children of both sexes. It helps to slow the bone aging and height growth rate so that it is near normal and to stop or reverse signs of early puberty. Synarel Nasal Solution decreases the testosterone hormones in boys and estrogen hormones in women and girls.

Synarel Nasal Solution is also prescribed for women who are infertile due to problems with their natural ovulation. It is used to desensitize the pituitary gland and stop the natural production of FSH and LH. Synthetic FSH, LH and hCG (gonadotrophins) are then administered to artificially stimulate ovulation.

Before Synarel Nasal Solution is Prescribed

Advise your doctor of all medical conditions and any Rx drugs or over-the-counter medications and supplements you may be taking before you begin treatment with Synarel Nasal Solution. You may need to take a pregnancy test before starting Synarel Nasal Spray as it may be harmful to your unborn or nursing baby. A barrier form of birth control, such as a condom, should be used while undergoing treatment with Synarel Nasal Solution, as hormonal contraception methods may not be effective in preventing a pregnancy.

Synarel Nasal Solution Precautions

The low estrogen state induced by Synarel Nasal Solution can cause a small amount of bone thinning, which may only partially recover after stopping treatment. Patients should discuss this possibility with their doctors and alert their doctors to conditions that they may have that could increase the risk of bone thinning. You should not use Synarel Nasal Solution if you have abnormal vaginal bleeding that has not been checked by a doctor.

Possible Side Effects of Synarel Nasal Solution

• Hot flashes
• Headaches
• Muscle pain
• Nasal irritation
• Vaginal dryness

Drugs Similar to Synarel Nasal Solution

• Aygestin
• Cyclomen
• Duphaston