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Buy Xeljanz XR Online

A prescription is required for this item.
No generic alternative is available at this time.
BRAND LISTING - Xeljanz XR (Tofacitinib Citrate)
Dosage Pack Size & Price Qty
Product description medically reviewed by Dr. Ami Patel, PharmD (Jan 30, 2020)

What is Xeljanz XR?

Xeljanz XR®, also known as Tofacitinib Citrate, is a Janus kinase (JAK) inhibitor that is in an extended-release (XR) form. JAKs are enzymes that transmit signals in response to increased levels of cytokines, which are proteins that are well-known contributors of inflammation in arthritic conditions. Increased JAK activity plays a key role in the immune response as it stimulates the production of proteins, some of which are pro-inflammatory. Xeljanz XR inhibits JAK activity and in doing so, disrupts inflammatory processes that are associated with arthritic conditions.

Conditions treated by Xeljanz XR?

Xeljanz XR is used to treat adults with moderate to severely active rheumatoid arthritis who did not respond to or could not tolerate methotrexate.

It is also used to treat active psoriatic arthritis in adults who did not respond to or could not tolerate methotrexate or similar medicines called nonbiologic disease-modifying antirheumatic drugs (DMARDs).

It may also be used to treat moderate to severely active ulcerative colitis in adults who did not respond to or could not tolerate tumor necrosis factor (TNF) blockers.

It is not known if this medication is safe and effective in adults with Hepatitis B or C, or children.

What are the side effects of Xeljanz XR?

The most common side effects that are associated with taking this medication include:

  • Rash
  • Diarrhea
  • Headache
  • Herpes zoster
  • Nasopharyngitis
  • Upper respiratory tract infection
  • Increased blood creatine phosphokinase
  • Increased cholesterol in blood

In addition, serious infections that can lead to hospitalization or death such as tuberculosis, as well as bacterial, fungal, viral, and other harmful infections, have developed in patients taking Xeljanz XR. If a serious infection develops, the treatment needs to be interrupted until the infection is under control.

Cases of lymphoma and other malignancies have also been observed in patients treated with Xeljanz XR. Furthermore, Epstein Barr virus-associated post-transplant lymphoproliferative disorder has been observed at increased rates in renal transplant patients who took Xeljanz XR and concomitant immunosuppressive medications.

What you should know before using Xeljanz XR

Before you buy Xeljanz XR online, the following factors should be considered:

Before treatment begins, patients need to be tested for latent tuberculosis. If the test is positive, treatment for tuberculosis should begin before starting Xeljanz XR. All patients need to be monitored for symptoms and signs of an infection during and after treatment with Xeljanz XR, even if the tuberculosis test is negative.

This medication is not recommended for patients with severe liver problems.

Rheumatoid arthritis patients who also demonstrate at least one cardiovascular risk factor generally have a higher rate of all-cause mortality and thrombosis when taking XELJANZ XR.

The use of XELJANZ XR should be avoided during a serious active infection, including localized infections.

Patients who are at risk of pulmonary, deep venous, and arterial thrombosis should avoid taking XELJANZ XR as this complication can become fatal if it occurs during treatment. Patients with symptoms of thrombosis should be promptly evaluated and treatment should be discontinued.

Use this medication with caution in patients who may be at an increased risk for gastrointestinal perforations.

Regular laboratory monitoring is recommended due to potential changes hemoglobin, lymphocytes, lipids, neutrophils, and liver enzymes.

The use of this drug should be avoided in patients who have had live vaccines (immunizations).

This medication is not recommended for nursing mothers. Information pertaining to the effects of Xeljanz XR in pregnant women is limited, but animal models indicate that the risk for potential harm to an unborn baby cannot be ruled out.

Xeljanz XR FAQ's

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  • The information provided on the website is intended to facilitate awareness about healthcare products and medical conditions generally but it is not a substitute for professional medical attention or advice. You should always speak with a qualified healthcare practitioner before taking any prescription or non-prescription drug.