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Buy Zycortal Online

A prescription is required for this item.
No generic alternative is available at this time.
BRAND LISTING - Zycortal (Desoxycorticosterone Pivalate)
Dosage Pack Size & Price Qty
25mg/mL (CAN origin)


Zycortal Description

You are the best source of information regarding your dog’s health when seeing your veterinarian for a regular check-up or when you believe something is not right. Your veterinarian will depend on you to describe the symptoms your dog is displaying. Tests should be performed before coming to a diagnosis of Addison’s disease, also called hypoadrenocorticism, if symptoms include weight loss, poor appetite, and trembling. This disease causes your dog’s adrenal glands to decrease the production of essential steroid hormones.

Regular Injections of Zycortal Will Help Relieve Symptoms of Addison’s

Zycortal with Desoxycorticosterone Pivalate is administered subcutaneously (just under the skin) every 25 days. Many veterinarians will instruct dog owners how to do this themselves at home to replace the aldosterone that is no longer being produced. Aldosterone regulates sodium and potassium levels, important electrolytes that help control blood pressure, heart function, and nervous system.

About Addison’s Disease

Addison’s disease can occur in any dog, no matter their age, size, or breed, although it is usually middle-aged females that are affected and a few breeds that may have a genetic predisposition for this disease. Zycortal is a newer injectable drug that can be administered to replace the mineralocorticoid hormones that are lacking in dogs with Addison’s disease, primarily it is aldosterone. You will also be required to give a glucocorticoid drug to your dog to replace the cortisol that is also missing.

What causes Addison’s disease? The reason is not entirely known, but it is believed to be due to a misguided immune system that signals the dog’s immune response to attack its own tissues, specifically the adrenal glands. This affects cortisol and aldosterone production. Cortisol is vital to maintain normal function of every organ and is responsible for normal appetite and the dog’s general well being. Aldosterone maintains proper levels of potassium and sodium in the bloodstream.

Before Zycortal is Prescribed

Tell your veterinarian if your dog is pregnant or nursing puppies before administering Zycortal as it may be harmful to the unborn or unweaned pups. Discuss other health issues your pet has and list any OTC or Rx meds you are currently giving, including vitamin supplements, to determine if Zycortal is compatible. You will also be instructed to give Prednisone or Prednisolone to your dog so learn about any side effects that may occur and follow directions given by your vet.

Zycortal Precautions

Keep all veterinarian appointments so your pet’s progress can be monitored and dose adjustments may be done, if required. Do not breed your dog but consider neutering or spaying as Zycortal is a life-time medication and could pose risks to pups. Keep Zycortal and the injection supplies out of children’s reach and all used needles/syringes should be kept in a proper ‘sharps’ container you can pick up at your local pharmacy for free and simply return it when it is full for another new one.

Possible Side Effects of Zycortal

  • Hair loss
  • Lethargic
  • Decreased appetite
  • Increased thirst/urination
  • Pain or redness at the injection site

Drugs Similar to Zycortal

The information provided on the website is intended to facilitate awareness about healthcare products and medical conditions generally but it is not a substitute for professional medical attention or advice. You should always speak with a qualified healthcare practitioner before taking any prescription or non-prescription drug.