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Buy Treximet Online

A prescription is required for this item.
GENERIC ALTERNATIVE LISTING - Sumatriptan Succinate/Naproxen Sodium
Dosage Pack Size & Price Qty
Brand medication is not available at this time.
Product description written by Dr. Ami Patel, PharmD (September 21, 2020)

What is Treximet?

Treximet (generic name Naproxen/Sumatriptan) is a pill used to get fast relief from a migraine headache. It contains two medications: naproxen, which is an NSAID (non-steroidal anti-inflammatory) and sumatriptan, which is a serotonin agonist (migraine medicine).

What is Treximet used for?

Treximet (Naproxen/Sumatriptan) is used by people over 12 years old to treat a migraine headache that has already started. It is not used to prevent new headaches, or decrease the number of headaches you may experience. Treximet has not been studied to treat or prevent other headaches (such as cluster headaches).

What are the side effects of Treximet?

A rare, but serious side effect of Treximet (Naproxen/Sumatriptan) includes an increased chance of having a heart attack or stroke. This is more likely if you are already at increased risk of heart problems, or if you have a personal history or family history of heart problems (including heart attack, stroke, or past heart surgery).

The most common Treximet side effects include:

  • feeling dizzy
  • having a dry mouth
  • feeling sick to your stomach
  • having heartburn
  • feeling hot
  • feeling weak or tired
  • feeling sleepy
  • tingling or numbness in your toes or fingers
  • having a stiff or painful chest, neck, jaw, or throat

Serious side effects from Treximet include: heart problems, liver problems, kidney problems, asthma attacks, stomach or gut problems, seizures, and problems with blood circulation.

If you notice any of the following serious Treximet side effects, call your doctor immediately:

  • Throwing up blood
  • Sudden or intense pain in your stomach
  • Sticky or dark stools
  • Bright red blood in stools
  • Loose or frequent stools
  • Unexpected weight gain
  • Pain in your upper right side
  • Swelling in your arms, legs, feet, or hands
  • Sudden Itching
  • Yellowing eyes or skin
  • Feeling unusually weak or tired
  • Unusual or unexpected nausea that’s not related to your headache
  • Feeling like you have the flu

This is not a full list of all possible Treximet side effects. Talk to your doctor if you think you are experiencing any side effects from Treximet.

What you should know before using Treximet (naproxen/sumatriptan).

Do not take Treximet (Naproxen/Sumatriptan) right after having heart surgery. Before taking Treximet, tell your doctor if you have any of the following medical conditions: high blood pressure, diabetes, high cholesterol, history of smoking, are overweight, drink alcohol, have asthma, had seizures, have liver problems, or have a family history of heart disease. Treximet is not for women who are pregnant or planning to become pregnant, or for women who are breastfeeding or are planning to breastfeed.

Be sure to tell your doctor about all other prescriptions and over-the-counter medicines you may be using (including vitamins, supplements and herbal drugs).

Tell your doctor about any allergies to any medications, including aspirin, before taking Treximet.


  • Why is Treximet so expensive?

    As a brand-name medication, Treximet may be expensive to purchase. If Treximet cost is a concern, consider using Treximet generic (Naproxen/Sumatriptan) as a lower priced alternative. Ask your doctor if Treximet generic is appropriate for you.

  • Where can I buy Treximet online?

    To lower your Treximet cost, buy Treximet online through a verified mail-order pharmacy such as Ask your doctor if Treximet generic (Naproxen/Sumatriptan) may be right for you.

  • The information provided on the website is intended to facilitate awareness about healthcare products and medical conditions generally but it is not a substitute for professional medical attention or advice. You should always speak with a qualified healthcare practitioner before taking any prescription or non-prescription drug.